Invitrogen™ TRAF3IP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529786

Catalog No. PIPA529786

Description

Recommended positive controls: HeLa, HepG2. Predicted reactivity: Mouse (99%), Rat (97%), Rabbit (97%), Rhesus Monkey (100%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Two alternative transcripts encoding different proteins have been identified. A third transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.

Specifications

• Antigen: TRAF3IP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TRAF3IP2
• Gene Alias: ACT1; adapter protein CIKS; AI429613; C6orf2; C6orf4; C6orf5; C6orf6; CANDF8; CIKS; connection to IKK and SAPK/JNK; NFkB-activating protein ACT1; nuclear factor NF-kappa-B activator 1; PSORS13; RGD1304768; RP3-487J7.3; TRAF3 interacting protein 2; TRAF3-interacting protein 2; TRAF3IP2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10758
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.87 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O43734
• Gene Symbols: TRAF3IP2
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human CIKS. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov