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Invitrogen™ TRAF3IP2 Polyclonal Antibody
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Catalog No. PIPA5110513
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100 μL
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PIPA5110513 100 μL
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Catalog No. PIPA5110513 Supplier Invitrogen™ Supplier No. PA5110513
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MPPQLQETRM NRSIPVEVDE SEPYPSQLLK PIPEYSPEEE SEPPAPNIRN MAPNSLSAPT MLHNSSGDFS QAHSTLKLAN HQRPVSRQVT CLRTQVLEDS EDSFCRRHPG LGKAFPSGCS AVSEPASESV VGALPAEHQF SFMEKRNQWL VSQLSAASPD TGHDSDKSDQ SLPNASADSL GGSQEMVQRP QPHRNRAGLD LPTIDTGYDS QPQDVLGIRQ LERPLPLTSV CYPQDLPRPL RSREFPQFEP QRYPACAQML PPNLSPHAPW NYHYHCPGSP DHQVPYGHDY PRAAYQQVIQ.

This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Two alternative transcripts encoding different proteins have been identified. A third transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRAF3IP2
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.68 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TRAF3IP2
Gene Accession No. O43734
Gene Alias ACT1; adapter protein CIKS; AI429613; C6orf2; C6orf4; C6orf5; C6orf6; CANDF8; CIKS; connection to IKK and SAPK/JNK; NFkB-activating protein ACT1; nuclear factor NF-kappa-B activator 1; PSORS13; RGD1304768; RP3-487J7.3; TRAF3 interacting protein 2; TRAF3-interacting protein 2; TRAF3IP2
Gene Symbols TRAF3IP2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TRAF3IP2 (NP_6717332).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 103213, 10758, 361857
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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