Invitrogen™ TRAF3IP2 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142292

Catalog No. PIPA5142292

Description

Additional Information: This antibody is expected to recognise reported isoforms 2 and 3 (NP_679211.1; NP_001157753.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:2,000.

This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Two alternative transcripts encoding different proteins have been identified. A third transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.

Specifications

• Antigen: TRAF3IP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TRAF3IP2
• Gene Alias: ACT1; adapter protein CIKS; AI429613; C6orf2; C6orf4; C6orf5; C6orf6; CANDF8; CIKS; connection to IKK and SAPK/JNK; NFkB-activating protein ACT1; nuclear factor NF-kappa-B activator 1; PSORS13; RGD1304768; RP3-487J7.3; TRAF3 interacting protein 2; TRAF3-interacting protein 2; TRAF3IP2
• Host Species: Goat
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 10758
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O43734
• Gene Symbols: TRAF3IP2
• Immunogen: Peptide with sequence C-PDTGHDSDKSDQ (aa 159-170).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov