Invitrogen™ TRAG3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA112868

Catalog No. 01-675-848

Description

This protein is expressed in various tumor cell lines including carcinomas, myeloid or lymphoid malignancies, melanomas or prostate cancer. It is also weakly expressed in kidney and overexpressed in taxol-resistant breast cancer line MDA 435(TR) or the doxorubicin-resistant multiple myelanoma lines 8226/Dox(40) or 8226/MDR(10)V.1.

The expression of the cancer-testis antigen Taxol resistanceassociated gene-3 (TRAG-3) is associated with acquired paclitaxel (Taxol) resistance, and is expressed in a variety of cancers - e.g., breast cancer, leukemia, and melanoma. Overexpressed in taxolresistant breast cancer line MDA 435(TR) and the doxorubicinresistant multiple myelanoma lines 8226/Dox(40) and 8226/MDR (10)V. Weakly expressed in kidney. TRAG-3 is an attractive target for immunotherapy of cancer.

Specifications

• Antigen: TRAG3
• Classification: Polyclonal
• Formulation: PBS with 0.08% sodium azide
• Gene Accession No.: Q9Y5P2
• Gene Symbols: CSAG2
• Immunogen: Synthetic peptide corresponding to human Trag-3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Gene: CSAG2
• Gene Alias: cancer/testis antigen 24.2; cancer/testis antigen family 24, member 2; chondrosarcoma-associated gene 2/3 protein; chondrosarcoma-associated gene 2/3 protein-like; CSAG family member 2; CSAG family, member 3B; CSAG2; CSAG3B; CT24.2; MGC149851; MGC149852; taxol resistance associated gene 3; taxol-resistant-associated gene 3 protein; trag 3; TRAG3; TRAG-3
• Host Species: Rabbit
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 102723547
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid