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Invitrogen™ TRAG3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA112868

Catalog No. 01-675-848


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Description

Description

This protein is expressed in various tumor cell lines including carcinomas, myeloid or lymphoid malignancies, melanomas or prostate cancer. It is also weakly expressed in kidney and overexpressed in taxol-resistant breast cancer line MDA 435(TR) or the doxorubicin-resistant multiple myelanoma lines 8226/Dox(40) or 8226/MDR(10)V.1.

The expression of the cancer-testis antigen Taxol resistanceassociated gene-3 (TRAG-3) is associated with acquired paclitaxel (Taxol) resistance, and is expressed in a variety of cancers - e.g., breast cancer, leukemia, and melanoma. Overexpressed in taxolresistant breast cancer line MDA 435(TR) and the doxorubicinresistant multiple myelanoma lines 8226/Dox(40) and 8226/MDR (10)V. Weakly expressed in kidney. TRAG-3 is an attractive target for immunotherapy of cancer.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TRAG3
Polyclonal
PBS with 0.08% sodium azide
Q9Y5P2
CSAG2
Synthetic peptide corresponding to human Trag-3.
100 μg
Primary
Human
Antibody
IgG
ELISA, Western Blot
Unconjugated
CSAG2
cancer/testis antigen 24.2; cancer/testis antigen family 24, member 2; chondrosarcoma-associated gene 2/3 protein; chondrosarcoma-associated gene 2/3 protein-like; CSAG family member 2; CSAG family, member 3B; CSAG2; CSAG3B; CT24.2; MGC149851; MGC149852; taxol resistance associated gene 3; taxol-resistant-associated gene 3 protein; trag 3; TRAG3; TRAG-3
Rabbit
Ammonium Sulfate Precipitation
RUO
102723547
-20°C, Avoid Freeze/Thaw Cycles
Liquid
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