Invitrogen™ Transferrin Polyclonal Antibody, FITC

Sheep Polyclonal Antibody

Supplier:  Invitrogen™ PA186736

Catalog No. PA186736

Description

PA1-86736 shows minimal cross reactivity with related serum proteins. Sheep anti Human transferrin antibody recognizes human transferrin, an approximately 80 kDa blood plasma glycoprotein synthesized by the liver, which contains two specific high affinity iron (Fe3+) binding sites and is responsible for the transport and supply of an exchangeable pool of iron, through binding to cell surface transferrin receptors.

Transferrins (Tf) are an approximately 80kDa blood plasma glycoprotein synthesized by the liver. They are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Transferrin is the primary blood iron transport protein and under normal conditions; approximately one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anaemia, iron overload and haemochromatosis.Serum transferrin may also have a further role in stimulating cell proliferation.

Specifications

• Antigen: Transferrin
• Classification: Polyclonal
• Conjugate: FITC
• Gene: Tf
• Gene Alias: AI266983; beta-1 metal-binding globulin; Cd176; DKFZp781D0156; epididymis secretory sperm binding protein Li 71p; HEL-S-71p; HP; hpx; hypotransferrinemia with hemochromatosis; ICA; Inhibitor of carbonic anhydrase; lactoferrin; liver regeneration-related protein LRRG03; liver transferrin; LOC100146633; PICA; porcine inhibitor of carbonic anhydrase; porcine inhibitor of carbonic anhydrase precursor; PRO1400; PRO1557; PRO2086; Serotransferrin; siderophilin; TF; Tfn; TFQTL1; transferin; Transferrin; transferrin precursor; Trf
• Host Species: Sheep
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 7018
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P02787
• Gene Symbols: Tf
• Immunogen: Pure human transferrin prepared from pooled normal human serum.
• Quantity: 1 mL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG