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Invitrogen™ Transferrin Receptor Monoclonal Antibody (OX-26)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA170033

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Catalog No. MA170033


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Description

Description

Transferrin Receptor Monoclonal Antibody for Western Blot, IHC (F), Flow, IP

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Transferrin Receptor
Monoclonal
1 mg/mL
PBS with 0.02% sodium azide
Q99376
TFRC
PHA activated lymph node cells of a PVG rat.
250 μg
Primary
Rat
Antibody
IgG2a
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
OX-26
Unconjugated
TFRC
2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
Mouse
Protein G
RUO
64678
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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