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Invitrogen™ Transferrin Receptor Monoclonal Antibody (R17217.1.4), FITC
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Catalog No. PIMA517922
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300 μg
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Catalog No. Quantity
PIMA517922 300 μg
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Catalog No. PIMA517922 Supplier Invitrogen™ Supplier No. MA517922
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Description

Rat Monoclonal Antibody

MA5-17922 targets CD71/transferrin receptor in FACS applications and shows reactivity with Mouse samples.

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Transferrin Receptor
Applications Flow Cytometry
Classification Monoclonal
Clone R17217.1.4
Concentration 0.1 mg/mL
Conjugate FITC
Formulation PBS with 4-5mg/mL BSA and 0.02% sodium azide
Gene TFRC
Gene Accession No. Q62351
Gene Alias 2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
Gene Symbols TFRC
Host Species Rat
Immunogen Friend erythroleukemia 745.6 induced for 5 days in 1.5% dimethyl sulfoxide.
Purification Method Protein G
Quantity 300 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22042
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Product Type Antibody
Form Liquid
Isotype IgG2a
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