Transferrin receptor Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-0616	100 μL

Catalog No. 50-198-0616 Supplier Bioss Supplier No. BS0988R

Description

Rabbit Polyclonal Antibody

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.

Specifications

• Antigen: Transferrin receptor
• Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: TFRC
• Gene Accession No.: P02786
• Gene Alias: 2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; TFR1; Tfrc; TR; transferrin receptor; transferrin receptor (p90, CD71); Transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
• Gene Symbols: TFRC
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human Transferrin receptor.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7037
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG