Invitrogen™ Transferrin Recombinant Mouse Monoclonal Antibody (TW4.20)

Mouse Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA548034

Catalog No. PIMA548034

Description

Specificity: Binds to the N-terminal domain of human transferrin.

Transferrins (Tf) are an approximately 80kDa blood plasma glycoprotein synthesized by the liver. They are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Transferrin is the primary blood iron transport protein and under normal conditions; approximately one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anaemia, iron overload and haemochromatosis.Serum transferrin may also have a further role in stimulating cell proliferation.

Specifications

• Antigen: Transferrin
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Gene Accession No.: P02787
• Gene Symbols: Tf
• Immunogen: Iron-free purified human transferrin.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA, Flow Cytometry, Inhibition Assays, Western Blot
• Clone: TW4.20
• Conjugate: Unconjugated
• Gene: Tf
• Gene Alias: AI266983; beta-1 metal-binding globulin; Cd176; DKFZp781D0156; epididymis secretory sperm binding protein Li 71p; HEL-S-71p; HP; hpx; hypotransferrinemia with hemochromatosis; ICA; Inhibitor of carbonic anhydrase; lactoferrin; liver regeneration-related protein LRRG03; liver transferrin; LOC100146633; PICA; porcine inhibitor of carbonic anhydrase; porcine inhibitor of carbonic anhydrase precursor; PRO1400; PRO1557; PRO2086; Serotransferrin; siderophilin; TF; Tfn; TFQTL1; transferin; Transferrin; transferrin precursor; Trf
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 7018
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid