Invitrogen™ Transthyretin Monoclonal Antibody (D2), Invitrogen™

Catalog No.	Quantity
FEMA550833	200 μL
FEMA550834	20 μL

Catalog No. FEMA550833 Supplier Invitrogen™ Supplier No. MA550833

Description

Mouse Monoclonal Antibody

Transthyretin (TTR), generally called prealbumin, is a plasma protein that plays an important role in physiology such as a transporter of hormone thyroxine and retinal-binding protein. After produced primarily in the liver, TTR is excreted into the plasma. TTR represents a disproportionate fraction (25%) of CSF protein, prompting the suggestion that it is either selectively transported across the blood-CSF barrier or synthesized de novo within the central nervous system. Transthyretin is a constituent found to the neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. It has been reported that more than 40 different mutations in the TTR gene associated with amyloid deposition.

Specifications

• Antigen: Transthyretin
• Applications: Western Blot, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: D2
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene: TTR
• Gene Accession No.: P02766
• Gene Alias: AA408768; AI787086; Amyloidosis I; ATTR; carpal tunnel syndrome 1; CTS; CTS1; D17860; epididymis luminal protein 111; HEL111; HsT2651; Lr1; PALB; prealbumin; pre-albumin; prealbumin, amyloidosis type I; Tbpa; thyroxine-binding prealbumin; transthyretin; Tt; TTR
• Gene Symbols: TTR
• Host Species: Mouse
• Immunogen: Recombinant Human PALB protein, Gly21-Glu147 (Accession #P02766).
• Purification Method: Protein A/G
• Quantity: 200 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7276
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1 κ