Invitrogen™ TRAP1 Monoclonal Antibody (3H4-2H6), FITC

Catalog No.	Quantity
PIMA545309	100 μg

Catalog No. PIMA545309

Supplier: Invitrogen™ MA545309

Description

Mouse Monoclonal Antibody

1 μg/mL of MA5-45309 was sufficient for detection of Trap-1/HSP75 in 20 μg of Human A431 lysate by ECL immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody. Detects approximately 75kDa.

The 90 kDa heat shock protein (hsp90) family of molecular chaperones is a highly conserved family of proteins that play an important physiological role. Hsp90 is involved in numerous cellular processes but is best known for its association with signal transduction machinery. A recently cloned homolog of hsp90 is the tumor necrosis factor receptor-associated protein (TRAP1). Like hsp90, TRAP1 is found to be associated with numerous proteins involved in diverse actions. Immunofluorescence data has shown TRAP1 to be localized in the mitochondria of mammalian cells. This observation and the fact that TRAP1 is shown to have a mitochondrial targeting presequence strongly implicates TRAP1 as a mitochondrial matrix protein.

Specifications

• Antigen: TRAP1
• Applications: Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: 3H4-2H6
• Concentration: 1 mg/mL
• Conjugate: FITC
• Formulation: PBS, 9.1mM sodium bicarbonate with 640.91mM DMSO, 136.36mM ethanolamine and no preservative; pH 7.4
• Gene: Trap1
• Gene Accession No.: Q12931, Q5XHZ0, Q9CQN1
• Gene Alias: 2410002K23Rik; heat shock protein 75 kDa, mitochondrial; HSP 75; HSP75; HSP90L; testicular tissue protein Li 209; TNF receptor associated protein 1; TNF receptor-associated protein 1; TNFR-associated protein 1; TRAP1; TRAP-1; tumor necrosis factor type 1 receptor associated protein; tumor necrosis factor type 1 receptor-associated protein
• Gene Symbols: Trap1
• Host Species: Mouse
• Immunogen: Purified recombinant TRAP1.
• Purification Method: Protein G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10131, 287069, 68015
• Target Species: Human, Mouse, Rat
• Content And Storage: 4°C, store in dark
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1 κ