Invitrogen™ TRAPPC10 Polyclonal Antibody

Catalog No.	Quantity
PIPA562189	100 μL

Catalog No. PIPA562189 Supplier Invitrogen™ Supplier No. PA562189

Description

Rabbit Polyclonal Antibody

Immunogen sequence: RAVVYSNTRE QSSEAALRIQ SSDKVTSISL PVAPAYHVIE FELEVLSLPS APALGGESDM LGMAEPHRKH KDKQRTGRCM VTTDHKVSID CPWSIYSTVI ALTFSVPFRT THSLLSSGTR KYVQVCVQNL S Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 83%.

TRAPPC10, also known as TMEM1 (transmembrane protein 1), EHOC1 (epilepsy holoprosencephaly candidate 1 protein) or GT334, is a widely expressed 1,259 amino acid protein that may function in vesicular transport. Despite its name, TRAPPC10 does not contain transmembrane domains. It is the human ortholog of the yeast Trs130 protein and its structure and function appears to be conserved. Localizing to the cis-Golgi apparatus, TRAPPC10 is believed to be involved in transport from the endoplasmic reticulum (ER) to the Golgi functioning as a component of the multisubunit transport protein particle (TRAPP) complex. Mutations in the gene encoding TRAPPC10 may be involved in autoimmune polyglandular disease type 1 or Unverricht-Lundborg disease, an autosomal recessive type of progressive myoclonic epilepsy.

Specifications

• Antigen: TRAPPC10
• Applications: Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: TRAPPC10
• Gene Accession No.: P48553
• Gene Alias: B230307C21Rik; EHOC1; EHOC-1; epilepsy holoprosencephaly candidate 1 protein; epilepsy holoprosencephaly candidate-1 protein; Gm870; GT334; Protein GT334; TMEM1; trafficking protein particle complex 10; trafficking protein particle complex subunit 10; trafficking protein particle complex subunit 10; LOW QUALITY PROTEIN: trafficking protein particle complex subunit 10; trafficking protein particle complex subunit 130; trafficking protein particle complex subunit TMEM1; transmembrane protein 1; transport protein particle subunit TMEM1; TRAPP 130 kDa subunit; TRAPP subunit TMEM1; trappc10; TRS130; TRS30; wu:fc21a02
• Gene Symbols: TRAPPC10
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human TRAPPC10. Recombinant protein control fragment (Product #RP-104221).
• Purification Method: Antigen Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7109
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG