Invitrogen™ TRAPPC5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104182

Catalog No. PIPA5104182

Description

Antibody detects endogenous levels of total TRAPPC5.

TRAPPC5 (trafficking protein particle complex 5), also known as TRS31, is a 181 amino acid protein belonging to the TRAPP (transport protein particle) small subunits family and the BET3 subfamily. Encoded by a gene that maps to human chromosome 19p13.2, TRAPPC5 is part of the multisubunit TRAPP tethering complex, which acts as a GTP exchange factor. Evolutionarily conserved, TRAPPC5 plays a role in protein binding,vesicle-mediated transport and nucleotide exchange stimulation. TRAPPC5 also performs guanine nucleotide exchanger factor (GEF) functions both in vitro and in vivo. Localizing to the Golgi apparatus, TRAPPC5 is essential for endoplasmic reticulum (ER)-to-Golgi and intra-Golgi vesicle trafficking in yeast, as well as additional transport events in mammals, such as post-Golgi trafficking.

Specifications

• Antigen: TRAPPC5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TRAPPC5
• Gene Alias: 4021401A16Rik; RGD1563971; trafficking protein particle complex 5; trafficking protein particle complex subunit 5; Trappc5; TRS31
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 126003, 363858, 66682
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8IUR0, Q9CQA1
• Gene Symbols: TRAPPC5
• Immunogen: A synthesized peptide derived from human TRAPPC5(Accession Q8IUR0), corresponding to amino acid residues T80-V130.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov