Invitrogen™ TRBP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555130

Catalog No. PIPA555130

Description

Immunogen sequence: MNELNSVSDL DRCHLYLMVL TELINLHLKV GWKRGNPIWR VISLLKNASI QHLQEMDSGQ EPTVGSQIQR VVSMAALAMV CEAIDQKPEL QLDSLHAG Highest antigen sequence identity to the following orthologs: Mouse - 64%, Rat - 59%.

The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1-a (EF-1-a), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.

Specifications

• Antigen: TRBP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TARBP1
• Gene Alias: Gm17296; Gm179; predicted gene, 17296; probable methyltransferase TARBP1; RP5-827C21.5; TAR (HIV) RNA binding protein 1; TAR (HIV) RNA-binding protein 1; TAR (HIV-1) RNA binding protein 1; TAR RNA loop binding protein; TAR RNA-binding protein 1; TAR RNA-binding protein of 185 kDa; Tarbp1; TRM3; tRNA methyltransferase 3 homolog; TRP185; TRP-185
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6894
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q13395
• Gene Symbols: TARBP1
• Immunogen: Recombinant protein corresponding to Human TRBP1. Recombinant protein control fragment (Product #RP-91765).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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