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Invitrogen™ TRBP1 Polyclonal Antibody
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Catalog No. PIPA5120744
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100 μL
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PIPA5120744 100 μL
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Catalog No. PIPA5120744 Supplier Invitrogen™ Supplier No. PA5120744
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QVESMHGAGN AKKNWQRIQE HFFFATFHPL KDYCLETIFY ILPRLSGLIE DEWITIDKFT RFTDVPLAAG FQWYLSQTQL SKLKPGDWSQ QDIGTNLVEA DNQAEWTDVQ KKIIPWNSRV SDLDLELLFQ DRAARLGKSI SRLIVVASLI DKPTNLGGLC RTCEVFGASV LVVGSLQCIS DKQFQHLSVS AEQWLPLVEV KPPQLIDYLQ QKKTEGYTII GVEQTAKSLD LTQYCFPEKS LLLLGNEREG IPANLIQQLD VCVEIPQQGI IRSLNVHVSG ALLIWEYTRQ QLLSHGDTKP.

The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1-a (EF-1-a), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRBP1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.847 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene TARBP1
Gene Accession No. Q13395
Gene Alias Gm17296; Gm179; predicted gene, 17296; probable methyltransferase TARBP1; RP5-827C21.5; TAR (HIV) RNA binding protein 1; TAR (HIV) RNA-binding protein 1; TAR (HIV-1) RNA binding protein 1; TAR RNA loop binding protein; TAR RNA-binding protein 1; TAR RNA-binding protein of 185 kDa; Tarbp1; TRM3; tRNA methyltransferase 3 homolog; TRP185; TRP-185
Gene Symbols TARBP1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1322-1621 of human TARBP1 (NP_005637.3).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6894
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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