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Invitrogen™ TREM1 Monoclonal Antibody (174031)
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Catalog No. PIMA523885
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100 μg
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Catalog No. Quantity
PIMA523885 100 μg
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Catalog No. PIMA523885 Supplier Invitrogen™ Supplier No. MA523885
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Description

Rat Monoclonal Antibody

In Western blots, no cross-reactivity with recombinant mouse TREM-2B, recombinant human (rh) TREM-1, or rhTREM-2 is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

TREM1 (triggering receptor expressed on myeloid cells 1) is a receptor belonging to the Ig superfamily that amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. It is thought that TREM1 other related TREM proteins such as TREM2 act to modulate the inflammatory response. TREM1 has also been linked to inflammatory bowel disease resulting in enhanced production of TNF, IL-6, IL-8, and MCP-1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TREM1
Applications Flow Cytometry, Functional Assay, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 174031
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene TREM1
Gene Accession No. Q9JKE2
Gene Alias CD354; sCD354; soluble CD354; soluble TREM 1; soluble TREM1; sTREM 1; sTREM1; TREM; Trem1; TREM-1; triggering receptor expressed in monocytes 1; triggering receptor expressed on monocytes 1; Triggering receptor expressed on myeloid cells; Triggering receptor expressed on myeloid cells 1
Gene Symbols TREM1
Host Species Rat
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse TREM-1 Ala21-Ser202.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 58217
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2a
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