Invitrogen™ TREM1 Monoclonal Antibody (CL7111)

Catalog No.	Quantity
PIMA535040	100 μL

Catalog No. PIMA535040 Supplier Invitrogen™ Supplier No. MA535040

Description

Mouse Monoclonal Antibody

Immunogen sequence: KLTEEKYELK EGQTLDVK Highest antigen sequence indentity to the following orthologs: Mouse - 71%, Rat - 71%.

TREM1 (triggering receptor expressed on myeloid cells 1) is a receptor belonging to the Ig superfamily that amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. It is thought that TREM1 other related TREM proteins such as TREM2 act to modulate the inflammatory response. TREM1 has also been linked to inflammatory bowel disease resulting in enhanced production of TNF, IL-6, IL-8, and MCP-1.

Specifications

• Antigen: TREM1
• Applications: Western Blot
• Classification: Monoclonal
• Clone: CL7111
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: TREM1
• Gene Accession No.: Q9NP99
• Gene Alias: CD354; sCD354; soluble CD354; soluble TREM 1; soluble TREM1; sTREM 1; sTREM1; TREM; Trem1; TREM-1; triggering receptor expressed in monocytes 1; triggering receptor expressed on monocytes 1; Triggering receptor expressed on myeloid cells; Triggering receptor expressed on myeloid cells 1
• Gene Symbols: TREM1
• Host Species: Mouse
• Immunogen: Synthetic Peptide corresponding to Human TREM1.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 54210
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1