Invitrogen™ Treslin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA538053

Catalog No. PIPA538053

Description

A recommended positive control is human small intestine tissue lysate. At least two isoforms of TICRR are known to exist.

Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC). Required to prevent mitotic entry after treatment with ionizing radiation.

Specifications

• Antigen: Treslin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TICRR
• Gene Alias: C15orf42; SLD3; TICRR; TOPBP1 interacting checkpoint and replication regulator; TOPBP1-interacting checkpoint and replication regulator; topBP1-interacting replication-stimulating protein; topBP1-interacting, replication-stimulating protein; Treslin
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 90381
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q7Z2Z1
• Gene Symbols: TICRR
• Immunogen: 19 amino acid peptide near the carboxy terminus of human TICRR.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov