Invitrogen™ Treslin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565560

Catalog No. PIPA565560

Description

Immunogen sequence: DIGVVEESPEK GDEISLRRSP RIKQLSFSRT HSASFYSVSQ PKSRSVQRVH SFQQDKSDQR ENSPVQSIRS PKSLLFGAMS EMISPSE Highest antigen sequence identity to the following orthologs - mouse 78%, rat 82%.

Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC). Required to prevent mitotic entry after treatment with ionizing radiation.

Specifications

• Antigen: Treslin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TICRR
• Gene Alias: C15orf42; SLD3; TICRR; TOPBP1 interacting checkpoint and replication regulator; TOPBP1-interacting checkpoint and replication regulator; topBP1-interacting replication-stimulating protein; topBP1-interacting, replication-stimulating protein; Treslin
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 90381
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q7Z2Z1
• Gene Symbols: TICRR
• Immunogen: Recombinant Human Treslin. Recombinant protein control fragment (Product #RP-106233).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG