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Invitrogen™ TRHR Polyclonal Antibody
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Catalog No. PIPA590309
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100 μL
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PIPA590309 100 μL
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Catalog No. PIPA590309 Supplier Invitrogen™ Supplier No. PA590309
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: YNLMSQKFRA AFRKLCNCKQ KPTEKPANYS VALNYSVIKE SDHFSTELDD ITVTDTYLSA TKVSFDDTCL ASEVSFSQS; Positive Samples: U-87MG; Cellular Location: Cell membrane, Multi-pass membrane protein.

TRH-R is a 398 amino acid integral membrane protein with six transmembrane domains and belongs to G-protein coupled receptor 1 family. It acts as a receptor for the signaling hormone TRH and activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon binding with TRH. Reports suggest that TRH-R is a neurotransmitter and neuro regulator that controls dimerization of the TRH receptor and potentiates hormone-induced receptor trafficking. It is known to widely express in the thyrotroph cells of the anterior pituitary.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRHR
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.81 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene TRHR
Gene Accession No. P34981
Gene Alias MGC141920; Thyroliberin receptor; thyrotropin releasing hormone receptor; thyrotropin-releasing hormone receptor; TRH receptor; TRH1 Receptor; Trhr; TRH-R; TRH-R1
Gene Symbols TRHR
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 320-398 of human TRHR (NP_0032921).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7201
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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