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Invitrogen™ TRIB1 Polyclonal Antibody
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Catalog No. PIPA5142357
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100 μg
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Catalog No. Quantity
PIPA5142357 100 μg
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Catalog No. PIPA5142357 Supplier Invitrogen™ Supplier No. PA5142357
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Description

Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.

TRIB1 also called gprotein coupled receptor induced, skip1, gig2, c8fwATP, functions in binding protein binding, protein kinase inhibitor activity, and protein serine/threonine kinase activities. Overexpression of TRIB1 in HeLa cells repressed the basal activity of the IL8 promoter by inhibiting AP1 activity. Overexpression of TRIB1 inhibited oncogenic Ras -driven AP1 activation and MEKK1-mediated AP1 activation. ERK activation was enhanced by TRIB1. Coimmunoprecipitation and yeast 2-hybrid assays showed that MEK1 interacted with both TRIB1 and TRIB3, and MKK4 interacted specifically with TRIB1. Cotransfection of MKK4 enhanced the level of TRIB1, indicating that the TRIB-MAPKK interaction stabilized TRIB1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRIB1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene TRIB1
Gene Accession No. Q96RU8
Gene Alias A530090O15Rik; C8FW; Gig2; GIG-2; G-protein-coupled receptor induced protein; G-protein-coupled receptor induced protein GIG2; G-protein-coupled receptor-induced gene 2 protein; G-protein-coupled receptor-induced protein 2; phosphoprotein regulated by mitogenic pathways; SKIP1; Trb1; TRB-1; Trib1; tribbles homolog 1; tribbles homolog 1 (Drosophila); tribbles pseudokinase 1; tribbles-like protein 1
Gene Symbols TRIB1
Host Species Goat
Immunogen Peptide with sequence C-TSDQIVPEYQEDSD (aa 353-366).
Purification Method Ammonium Sulfate Precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10221
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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