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Invitrogen™ TRIB2 Monoclonal Antibody (1D11)
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Catalog No. PIMA524548
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100 μg
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Catalog No. Quantity
PIMA524548 100 μg
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Catalog No. PIMA524548 Supplier Invitrogen™ Supplier No. MA524548
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Description

Mouse Monoclonal Antibody

Peptide Sequence: MNIHRSTPIT IARYGRSRNK TQDFEELSSI RSAEPSQSFS PNLGSPSPPE TPNLSHCVSC IGKYLLLEPL EGDHVFRAVH LHSGEELVCK VFDISCYQES LAPCFCLSAH SNINQITEII LGETKAYVFF ERSYGDMHSF VRTCKKLREE EAARLFYQIA SAVAHCHDGG LVLRDLKLRK FIFKDEERTR VKLESLEDAY ILRGDDDSLS DKHGCPAYVS PEILNTSGSY SGKAADVWSL GVMLYTMLVG RYPFHDIEPS SLFSKIRRGQ FNIPETLSPK AKCLIRSILR REPSERLTSQ EILDHPWFST DFSVSNSAYG AKEVSDQLVP DVNMEENLDP FFN.

This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRIB2
Applications ELISA, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 1D11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene Trib2
Gene Accession No. Q92519
Gene Alias AW319517; C5FW; GS3955; RGD1564451; TRB2; TRB-2; trib2; TRIB2 (HGNC:30809); Tribbles homolog 2; tribbles homolog 2 (Drosophila); tribbles pseudokinase 2
Gene Symbols Trib2
Host Species Mouse
Immunogen TRIB2 (AAH02637, 1 a.a. ~ 343 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 28951
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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