Invitrogen™ TRIB2 Monoclonal Antibody (OTI8D11)

Catalog No.	Quantity
PIMA524942	100 μL

Catalog No. PIMA524942 Supplier Invitrogen™ Supplier No. MA524942

Description

Mouse Monoclonal Antibody

TRIB2 Monoclonal Antibody for Western Blot, ICC/IF, IHC (P), Flow

This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.

Specifications

• Antigen: TRIB2
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: OTI8D11
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: Trib2
• Gene Accession No.: Q92519
• Gene Alias: AW319517; C5FW; GS3955; RGD1564451; TRB2; TRB-2; trib2; TRIB2 (HGNC:30809); Tribbles homolog 2; tribbles homolog 2 (Drosophila); tribbles pseudokinase 2
• Gene Symbols: Trib2
• Host Species: Mouse
• Immunogen: Full length human recombinant protein of TRIB2 produced in HEK293T cell.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 28951
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b