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Invitrogen™ TRIB2 Polyclonal Antibody
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Catalog No. PIPA551555
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100 μL
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PIPA551555 100 μL
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Catalog No. PIPA551555 Supplier Invitrogen™ Supplier No. PA551555
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TIARYGRSRN KTQDFEELSS IRSAEPSQSF SPNLGSPSPP ETPNLSHCVS CIGKYLLLEP LEGDHVFRAV HLHSGEELVC KVFDISCYQE SLAPCFCLSA HSNINQITEI ILGETKAYVF FERSYGDMHS FVRTCKKLRE Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 41%.

This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRIB2
Applications Immunocytochemistry, Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Trib2
Gene Accession No. Q92519
Gene Alias AW319517; C5FW; GS3955; RGD1564451; TRB2; TRB-2; trib2; TRIB2 (HGNC:30809); Tribbles homolog 2; tribbles homolog 2 (Drosophila); tribbles pseudokinase 2
Gene Symbols Trib2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TRIB2. Recombinant protein control fragment (Product #RP-95138).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 28951
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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