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TRIB2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987164
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50-198-7164 100 μL
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Catalog No. 50-198-7164 Supplier Bioss Supplier No. BS6262R
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Rabbit Polyclonal Antibody

This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.

Specifications

Antigen TRIB2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Trib2
Gene Accession No. Q92519
Gene Alias AW319517; C5FW; GS3955; RGD1564451; TRB2; TRB-2; TRIB2; TRIB2 (HGNC:30809); Tribbles homolog 2; tribbles homolog 2 (Drosophila); tribbles pseudokinase 2
Gene Symbols Trib2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human TRIB2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 28951
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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