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Invitrogen™ TRIF Monoclonal Antibody (OTI1G7)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA526477
Description
TRIF Monoclonal Antibody for Western Blot
Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.
Specifications
TRIF | |
Monoclonal | |
1 mg/mL | |
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q8IUC6 | |
TICAM1 | |
Human recombinant protein fragment corresponding to amino acids 120-420 of TICAM1 produced in E.coli. | |
100 μL | |
Primary | |
Human, Monkey | |
Antibody | |
IgG1 |
Western Blot | |
OTI1G7 | |
Unconjugated | |
TICAM1 | |
AW046014; AW547018; hCG_39321; HSD34; IIAE6; MyD88-3; Proline-rich, vinculin and TIR domain-containing protein B; PRVTIRB; Putative NF-kappa-B-activating protein 502H; RNF36; TI; Ticam1; TICAM-1; TIR domain containing adaptor inducing interferon-beta; TIR domain-containing adapter molecule 1; TIR domain-containing adapter protein inducing IFN-beta; TIR domain-containing adaptor inducing interferon-beta; TIR-domain containing adaptor inducing interferon-beta; toll like receptor adaptor molecule 1; toll-interleukin 1 receptor domain-containing adapter protein inducing interferon-beta; toll-interleukin I receptor domain containing adaptor molecule 1; toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta; toll-like receptor adaptor molecule 1; TRIF | |
Mouse | |
Affinity chromatography | |
RUO | |
148022 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
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