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Invitrogen™ TRIF Monoclonal Antibody (OTI1G7)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526477

Catalog No. PIMA526477


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Description

Description

TRIF Monoclonal Antibody for Western Blot

Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TRIF
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q8IUC6
TICAM1
Human recombinant protein fragment corresponding to amino acids 120-420 of TICAM1 produced in E.coli.
100 μL
Primary
Human, Monkey
Antibody
IgG1
Western Blot
OTI1G7
Unconjugated
TICAM1
AW046014; AW547018; hCG_39321; HSD34; IIAE6; MyD88-3; Proline-rich, vinculin and TIR domain-containing protein B; PRVTIRB; Putative NF-kappa-B-activating protein 502H; RNF36; TI; Ticam1; TICAM-1; TIR domain containing adaptor inducing interferon-beta; TIR domain-containing adapter molecule 1; TIR domain-containing adapter protein inducing IFN-beta; TIR domain-containing adaptor inducing interferon-beta; TIR-domain containing adaptor inducing interferon-beta; toll like receptor adaptor molecule 1; toll-interleukin 1 receptor domain-containing adapter protein inducing interferon-beta; toll-interleukin I receptor domain containing adaptor molecule 1; toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta; toll-like receptor adaptor molecule 1; TRIF
Mouse
Affinity chromatography
RUO
148022
-20°C, Avoid Freeze/Thaw Cycles
Liquid
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