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TRIF (TICAM-1) Mouse anti-Human, PE, Clone: U19-709, BD

Catalog No. BDB566354 Shop All BD Biosciences Products
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BDB566354 50 μg
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Catalog No. BDB566354 Supplier BD Biosciences Supplier No. 566354
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Description

Mouse Monoclonal Antibody

The U19-709 monoclonal antibody specifically recognizes TIR domain-containing adapter inducing IFN-β (TRIF),which is also known as TIR domain-containing adapter molecule 1 (TICAM-1). TRIF (TICAM-1) is an intracellular adaptor protein that contains a Toll/Interleukin-1 Receptor (TIR) homology domain. Double stranded RNA (dsRNA)-bound Toll-like receptor 3 (TLR3/CD283) or lipopolysaccharide (LPS)-triggered TLR4/CD284 can interact with TRIF (TICAM-1). This leads to downstream signaling cascades involving Interferon regulatory factors (eg, IRF3 or IRF7) or nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) that induce Interferon-beta (IFN-β) expression.

R-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae. It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule. This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRIF (TICAM-1)
Classification Monoclonal
Clone U19-709
Concentration 0.2mg/mL
Conjugate PE
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Gene Alias TICAM1, PRVTIRB, MyD88-3, IIAE6
Host Species Mouse
Immunogen Human TRIF Recombinant Protein
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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