Invitrogen™ TRIM22 Monoclonal Antibody (OTI1D3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526093

Catalog No. PIMA526093

Description

TRIM22 Monoclonal Antibody for Western Blot, IHC (P)

TRIM22 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. It localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects.

Specifications

• Antigen: TRIM22
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8IYM9
• Gene Symbols: TRIM22
• Immunogen: Human recombinant protein fragment corresponding to amino acids 61-406 of TRIM22 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1D3
• Conjugate: Unconjugated
• Gene: TRIM22
• Gene Alias: 50 kDa-stimulated trans-acting factor; E3 ubiquitin-protein ligase TRIM22; GPSTAF50; RING finger protein 94; RING-type E3 ubiquitin transferase TRIM22; RNF94; STAF50; Staf-50; stimulated trans-acting factor (50 kDa); TRIM22; tripartite binding motif 22; tripartite motif containing 22; tripartite motif protein TRIM22; tripartite motif-containing 22; tripartite motif-containing protein 22
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10346
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid