TRIM22 Mouse anti-Human, Clone: OTI1D3, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF505253

Catalog No. 50-166-3504

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

TRIM22 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. It localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon′s antiviral effects. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon′s antiviral effects.

Specifications

• Antigen: TRIM22
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: TRIM22
• Gene Alias: GPSTAF50, RNF94, STAF50
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10346
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1D3
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q8IYM9
• Gene Symbols: TRIM22
• Immunogen: Human recombit protein fragment corresponding to amino acids 61-406 of human TRIM22 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1