Invitrogen™ TRIM22 Polyclonal Antibody

Catalog No.	Quantity
PI720263	100 μg

Catalog No. PI720263 Supplier Invitrogen™ Supplier No. 720263

Description

Rabbit Polyclonal Antibody

These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature. This antibody is predicted to react with Monkey, Horse and Bat.

TRIM22 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. It localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects.

Specifications

• Antigen: TRIM22
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2-7.4
• Gene: TRIM22
• Gene Accession No.: Q8IYM9
• Gene Alias: 50 kDa-stimulated trans-acting factor; E3 ubiquitin-protein ligase TRIM22; GPSTAF50; RING finger protein 94; RING-type E3 ubiquitin transferase TRIM22; RNF94; STAF50; Staf-50; stimulated trans-acting factor (50 kDa); TRIM22; tripartite binding motif 22; tripartite motif containing 22; tripartite motif protein TRIM22; tripartite motif-containing 22; tripartite motif-containing protein 22
• Gene Symbols: TRIM22
• Host Species: Rabbit
• Immunogen: Peptides corresponding to Human TRIM22 (aa 79-96, 151-170).
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10346
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG