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Invitrogen™ TRIM22 Polyclonal Antibody
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Catalog No. PIPA551964
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100 μL
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PIPA551964 100 μL
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Catalog No. PIPA551964 Supplier Invitrogen™ Supplier No. PA551964
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: NEVVKECQEK LQVALQRLIK EDQEAEKLED DIRQERTAWK NYIQIERQKI LKGFNEMRVI LDNEEQRELQ KLEEGEVNVL DNLAAATDQL VQQRQDASTL ISDLQRRLRG SSVEMLQDVI DVMKRSESWT LKKPKSVSKK LKSVFRV Highest antigen sequence identity to the following orthologs: Mouse - 54%, Rat - 54%.

TRIM22 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. It localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRIM22
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TRIM22
Gene Accession No. Q8IYM9
Gene Alias 50 kDa-stimulated trans-acting factor; E3 ubiquitin-protein ligase TRIM22; GPSTAF50; RING finger protein 94; RING-type E3 ubiquitin transferase TRIM22; RNF94; STAF50; Staf-50; stimulated trans-acting factor (50 kDa); TRIM22; tripartite binding motif 22; tripartite motif containing 22; tripartite motif protein TRIM22; tripartite motif-containing 22; tripartite motif-containing protein 22
Gene Symbols TRIM22
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TRIM22. Recombinant protein control fragment (Product #RP-102255).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10346
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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