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Invitrogen™ TRIM23 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA597010
Description
Immunogen sequence: MATLVVNKLG AGVDSGRQGS RGTAVVKVLE CGVCEDVFSL QGDKVPRLLL CGHTVCHDCL TRLPLHGRAI RCPFDRQVTD LGDSGVWGLK KNFALLELLE RLQNGPIGQY GAAEESIGIS GESIIRCDED EAHLASVYCT VCATHLCSEC SQVTHSTKTL AKHRRVPLAD KPHEKTMCSQ HQVHAIEFVC LEEGCQTSPL MCCVCKEYGK HQGHKHSVLE PEANQIRASI LDMAHCIRTF TEEISDYSRK LVGIVQHIEG GEQIVEDGIG MAHTEHVPGT; Positive Samples: PC-12, Mouse spleen, Mouse brain; Cellular Location: Endomembrane system, Golgi apparatus membrane, Lysosome membrane.
Acts as an E3 ubiquitin-protein ligase. In the presence of the human cytomegalovirus (HCMV) protein UL144, participates in 'Lys-63'-linked auto-ubiquitination of TRAF6 resulting in the virally controlled activation of NF-kappa-B at early time of infection. The C-terminus can act as an allosteric activator of the cholera toxin catalytic subunit.
Specifications
TRIM23 | |
Polyclonal | |
Unconjugated | |
TRIM23 | |
6330516O20Rik; ADP-ribosylation factor domain protein 1; ADP-ribosylation factor domain protein 1 64kD; ADP-ribosylation factor domain protein 1, 64kD; ADP-ribosylation factor domain protein 1, 64kDa; ADP-ribosylation factor domain-containing protein 1; AI450195; ARD1; Ard-1; ARF domain protein 1; ARFD1; E3 ubiquitin-protein ligase TRIM23; GTP-binding protein ARD-1; nucleotide binding protein; RING finger protein 46; RING-type E3 ubiquitin transferase TRIM23; RNF46; TRIM23; tripartite motif containing 23; tripartite motif protein 23; tripartite motif protein TRIM23; tripartite motif-containing 23; tripartite motif-containing protein 23 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
373, 81002, 81003 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Western Blot, Immunocytochemistry | |
0.73 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P36406, P36407, Q8BGX0 | |
TRIM23 | |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TRIM23 (NP_0016471). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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