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Invitrogen™ TRIM23 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597010

Catalog No. PIPA597010


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Description

Description

Immunogen sequence: MATLVVNKLG AGVDSGRQGS RGTAVVKVLE CGVCEDVFSL QGDKVPRLLL CGHTVCHDCL TRLPLHGRAI RCPFDRQVTD LGDSGVWGLK KNFALLELLE RLQNGPIGQY GAAEESIGIS GESIIRCDED EAHLASVYCT VCATHLCSEC SQVTHSTKTL AKHRRVPLAD KPHEKTMCSQ HQVHAIEFVC LEEGCQTSPL MCCVCKEYGK HQGHKHSVLE PEANQIRASI LDMAHCIRTF TEEISDYSRK LVGIVQHIEG GEQIVEDGIG MAHTEHVPGT; Positive Samples: PC-12, Mouse spleen, Mouse brain; Cellular Location: Endomembrane system, Golgi apparatus membrane, Lysosome membrane.

Acts as an E3 ubiquitin-protein ligase. In the presence of the human cytomegalovirus (HCMV) protein UL144, participates in 'Lys-63'-linked auto-ubiquitination of TRAF6 resulting in the virally controlled activation of NF-kappa-B at early time of infection. The C-terminus can act as an allosteric activator of the cholera toxin catalytic subunit.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TRIM23
Polyclonal
Unconjugated
TRIM23
6330516O20Rik; ADP-ribosylation factor domain protein 1; ADP-ribosylation factor domain protein 1 64kD; ADP-ribosylation factor domain protein 1, 64kD; ADP-ribosylation factor domain protein 1, 64kDa; ADP-ribosylation factor domain-containing protein 1; AI450195; ARD1; Ard-1; ARF domain protein 1; ARFD1; E3 ubiquitin-protein ligase TRIM23; GTP-binding protein ARD-1; nucleotide binding protein; RING finger protein 46; RING-type E3 ubiquitin transferase TRIM23; RNF46; TRIM23; tripartite motif containing 23; tripartite motif protein 23; tripartite motif protein TRIM23; tripartite motif-containing 23; tripartite motif-containing protein 23
Rabbit
Affinity Chromatography
RUO
373, 81002, 81003
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Western Blot, Immunocytochemistry
0.73 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P36406, P36407, Q8BGX0
TRIM23
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TRIM23 (NP_0016471).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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