TRIM23 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA534624

Catalog No. PIPA534624

Description

Recommended positive controls: HeLaS3. Predicted reactivity: Rhesus Monkey (100%). IHC notes, Requires antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Acts as an E3 ubiquitin-protein ligase. In the presence of the human cytomegalovirus (HCMV) protein UL144, participates in 'Lys-63'-linked auto-ubiquitination of TRAF6 resulting in the virally controlled activation of NF-kappa-B at early time of infection. The C-terminus can act as an allosteric activator of the cholera toxin catalytic subunit.

Specifications

• Antigen: TRIM23
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TRIM23
• Gene Alias: 6330516O20Rik; ADP-ribosylation factor domain protein 1; ADP-ribosylation factor domain protein 1 64kD; ADP-ribosylation factor domain protein 1, 64kD; ADP-ribosylation factor domain protein 1, 64kDa; ADP-ribosylation factor domain-containing protein 1; AI450195; ARD1; Ard-1; ARF domain protein 1; ARFD1; E3 ubiquitin-protein ligase TRIM23; GTP-binding protein ARD-1; nucleotide binding protein; RING finger protein 46; RING-type E3 ubiquitin transferase TRIM23; RNF46; TRIM23; tripartite motif containing 23; tripartite motif protein 23; tripartite motif protein TRIM23; tripartite motif-containing 23; tripartite motif-containing protein 23
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 373, 81003
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.67 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P36406, Q8BGX0
• Gene Symbols: TRIM23
• Immunogen: Synthetic peptide corresponding to a region within amino acids 1 and 44 of TRIM23 (Uniprot ID#P36406)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG