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Invitrogen™ TRIM24 Polyclonal Antibody
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Catalog No. PIPA587975
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100 μL
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PIPA587975 100 μL
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Catalog No. PIPA587975 Supplier Invitrogen™ Supplier No. PA587975
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DGKAFGSPMI DLSSPVGGSY NLPSLPDIDC SSTIMLDNIV RKDTNIDHGQ PRPPSNRTVQ SPNSSVPSPG LAGPVTMTSV HPPIRSPSAS SVGSRGSSGS SSKPAGADST HKVPVVMLEP IRIKQENSGP PENYDFPVVI VKQESDEESR PQNANYPRSI LTSLLLNSSQ SSTSEETVLR SDAPDSTGDQ PGLHQDNSSN GKSEWLDPSQ KSPLHVGETR K; Positive Samples: LO2, MCF-7, HeLa, 293T, HT-29; Cellular Location: Cytoplasm, Nucleus.

The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRIM24
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.51 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene TRIM24
Gene Accession No. O15164
Gene Alias A130082H20Rik; Ab2-427; AI447469; D430004I05Rik; E3 ubiquitin-protein ligase TRIM24; hTIF1; PTC6; RING finger protein 82; RING-type E3 ubiquitin transferase TIF1-alpha; RNF82; TF1A; Tif1; Tif1a; TIF1alpha; TIF1-alpha; Transcription intermediary factor 1-alpha; transcriptional intermediary factor 1; transcriptional intermediary factor 1, alpha; Trim24; tripartite motif containing 24; tripartite motif-containing 24; tripartite motif-containing protein 24
Gene Symbols TRIM24
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 600-820 of human TRIM24 (NP_0569892).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8805
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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