TRIM24 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA530286

Catalog No. PIPA530286

Description

Recommended positive controls: HeLa. Predicted reactivity: Mouse (99%), Xenopus laevis (86%), Rhesus Monkey (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Specifications

• Antigen: TRIM24
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TRIM24
• Gene Alias: A130082H20Rik; Ab2-427; AI447469; D430004I05Rik; E3 ubiquitin-protein ligase TRIM24; hTIF1; PTC6; RING finger protein 82; RING-type E3 ubiquitin transferase TIF1-alpha; RNF82; TF1A; Tif1; Tif1a; TIF1alpha; TIF1-alpha; Transcription intermediary factor 1-alpha; transcriptional intermediary factor 1; transcriptional intermediary factor 1, alpha; Trim24; tripartite motif containing 24; tripartite motif-containing 24; tripartite motif-containing protein 24
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8805
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.55 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O15164
• Gene Symbols: TRIM24
• Immunogen: Recombinant fragment corresponding to a region within amino acids 82 and 399 of Human TIF1 alpha
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov