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Invitrogen™ TRIM5 alpha Monoclonal Antibody (3B11H2)
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Catalog No. PIMA515232
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100 μL
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PIMA515232 100 μL
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Catalog No. PIMA515232 Supplier Invitrogen™ Supplier No. MA515232
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Description

Mouse Monoclonal Antibody

MA5-15232 targets Trim5a in indirect ELISA, IHC and WB applications and shows reactivity with Human samples. The MA5-15232 immunogen is purified recombinant fragment of human trim5 alpha expressed in E. Coli.

The protein encoded by this gene is a member of the tripartite motif family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coiled-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiquitinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRIM5 alpha
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 3B11H2
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene Trim5
Gene Accession No. Q9C035
Gene Alias EG667823; Gm8833; HGNC:16276; OTTHUMP00000069812; RING finger protein 88; RING-type E3 ubiquitin transferase TRIM5; RNF88; TRIM5; Trim5 alpha; TRIM5 alpha; predicted E3 ubiquiting ligase; TRIM5 gamma; predicted E3 ubiquiting ligase; trim5a; TRIM5alpha; tripartite motif containing 5; tripartite motif containing 5 transcript variant iota; tripartite motif containing 5 transcript variant kappa; tripartite motif protein TRIM5; tripartite motif-containing 5; tripartite motif-containing 5 alpha isoform; tripartite motif-containing 5 gamma isoform; tripartite motif-containing 5/cyclophilin A fusion protein; tripartite motif-containing protein 5; tripartite motif-containing protein 5 isoform alpha
Gene Symbols Trim5
Host Species Mouse
Immunogen Purified recombinant fragment of human trim5 alpha expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 85363
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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