Invitrogen™ TRIM5 alpha Monoclonal Antibody (3B11H2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515232

Catalog No. PIMA515232

Description

MA5-15232 targets Trim5a in indirect ELISA, IHC and WB applications and shows reactivity with Human samples. The MA5-15232 immunogen is purified recombinant fragment of human trim5 alpha expressed in E. Coli.

The protein encoded by this gene is a member of the tripartite motif family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coiled-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiquitinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Specifications

• Antigen: TRIM5 alpha
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Ascites with 0.03% sodium azide
• Gene Accession No.: Q9C035
• Gene Symbols: Trim5
• Immunogen: Purified recombinant fragment of human trim5 alpha expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 85363
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 3B11H2
• Conjugate: Unconjugated
• Gene: Trim5
• Gene Alias: EG667823; Gm8833; HGNC:16276; OTTHUMP00000069812; RING finger protein 88; RING-type E3 ubiquitin transferase TRIM5; RNF88; TRIM5; Trim5 alpha; TRIM5 alpha; predicted E3 ubiquiting ligase; TRIM5 gamma; predicted E3 ubiquiting ligase; trim5a; TRIM5alpha; tripartite motif containing 5; tripartite motif containing 5 transcript variant iota; tripartite motif containing 5 transcript variant kappa; tripartite motif protein TRIM5; tripartite motif-containing 5; tripartite motif-containing 5 alpha isoform; tripartite motif-containing 5 gamma isoform; tripartite motif-containing 5/cyclophilin A fusion protein; tripartite motif-containing protein 5; tripartite motif-containing protein 5 isoform alpha
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1