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Invitrogen™ TRIM67 Polyclonal Antibody
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Catalog No. PIPA557056
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100 μL
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PIPA557056 100 μL
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Catalog No. PIPA557056 Supplier Invitrogen™ Supplier No. PA557056
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VCGSLFREPI ILPCSHNVCL PCARTIAVQT PDGEQHLPQP LLLSRGSGLQ AGAAAAASLE HDAAAGPACG GAGGSAA Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 81%.

The TRIM67 gene encodes a member of the tripartite motif (TRIM) protein family, which is involved in various cellular processes including protein ubiquitination, signal transduction, and immune responses. TRIM67 contains RING, B-box, and coiled-coil domains, characteristic of TRIM proteins, which facilitate interactions with other proteins and contribute to its role in ubiquitination and cellular regulation. TRIM67 is notably expressed in the brain and has been associated with neurodevelopmental processes, particularly influencing neuronal differentiation and synapse formation. This gene plays a regulatory role in signaling pathways that are critical for neural development, and mutations or dysregulation in TRIM67 have been linked to neurodevelopmental disorders and cognitive deficits. Additionally, TRIM67's involvement in protein degradation and signal modulation may impact cellular architecture and brain function. Ongoing research seeks to elucidate TRIM67's precise mechanisms and potential therapeutic targets for neurological conditions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRIM67
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TRIM67
Gene Accession No. Q6ZTA4
Gene Alias D130049O21Rik; RGD1560667; TNL; Trim67; TRIM9-like protein; TRIM9-like protein TNL; tripartite motif containing 67; tripartite motif-containing 67; tripartite motif-containing protein 67
Gene Symbols TRIM67
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TRIM67. Recombinant protein control fragment (Product #RP-94143).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 440730
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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