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Invitrogen™ TRIM72 Polyclonal Antibody, Biotin
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Catalog No. PIPA5142623
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100 μg
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Catalog No. Quantity
PIPA5142623 100 μg
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Catalog No. PIPA5142623 Supplier Invitrogen™ Supplier No. PA5142623
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Description

Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.

Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRIM72
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Biotin
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene TRIM72
Gene Accession No. Q1XH17
Gene Alias BC067209; mg53; mitsugumin 53; mitsugumin-53; RGD1562778; TRIM72; trim72 {ECO:0000250; tripartite motif containing 72; tripartite motif containing 72, E3 ubiquitin protein ligase; tripartite motif-containing 72; tripartite motif-containing protein 72; UniProtKB:Q8N4X6}
Gene Symbols TRIM72
Host Species Goat
Immunogen Peptide with sequence C-RPQALSTNLQ (aa 61-70).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 434246
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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