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Invitrogen™ TRIM74 Polyclonal Antibody
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Catalog No. PA550812
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100 μL
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PA550812 100 μL
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Catalog No. PA550812 Supplier Invitrogen™ Supplier No. PA550812
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total TRIM74 protein.

TRIM 74 (Tripartite motif-containing protein 74) is a possible protein coding regions found at gene location 7q11.23. Tripartite motif (TRIM) proteins play important roles in a variety of cellular functions including cell proliferation, differentiation, development, oncogenesis, and apoptosis. TRIM gene expression analysis in primary human immune cells seem to suggest the involvement of TRIM proteins in also regulating host antiviral activities. The gene encoding TRIM 74 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRIM74
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 2.7 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene TRIM74
Gene Accession No. Q86UV6
Gene Alias TRIM50C; TRIM74; tripartite motif containing 74; tripartite motif-containing 50C; tripartite motif-containing 74; tripartite motif-containing protein 50C; Tripartite motif-containing protein 74
Gene Symbols TRIM74
Host Species Rabbit
Immunogen Full length fusion protein of Human TRIM74.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 378108
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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