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Invitrogen™ TRIP10 Polyclonal Antibody
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Catalog No. PIPA5121057
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100 μL
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PIPA5121057 100 μL
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Catalog No. PIPA5121057 Supplier Invitrogen™ Supplier No. PA5121057
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Description

Rabbit Polyclonal Antibody

Positive test controls include: HepG2, HeLa, SKOV3, A673, 5637, Mouse kidney, Mouse heart, Mouse lung. The target is usually found in the following locations: Cell membrane, Cell projection, Cytoplasm, Golgi apparatus, Lysosome, cell cortex, cytoskeleton, perinuclear region, phagocytic cup. Immunogen sequence: AKCLEGMKVA ANAVDPKNDS HVLIELHKSG FARPGDVEFE DFSQPMNRAP SDSSLGTPSD GRPELRGPGR SRTKRWPFGK KNKTVVTEDF SHLPPEQQRK RLQQQLEERS RELQKEVDQR EALKKMKDVY EKTPQMGDPA SLEPQIAETL SNIERLKLEV QKYEAWLAEA ESRVLSNRGD SLSRHARPPD PPASAPPDSS SNSASQDTKE SSEEPPSEES QDTPIYTEFD EDFEEEPTSP IGHCVAIYHF EGSSEGTISM AEGEDLSLME EDKGDGWTRV RRKEGGEGYV PTSYLRVTLN.

Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling. Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRIP10
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.19 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Trip10
Gene Accession No. Q15642, Q8CJ53
Gene Alias AI646975; Cdc42 interacting protein-4; cdc42-interacting protein 4; Cip4; hSTP; protein Felic; Salt tolerant protein; salt tolerator; STOT; STP; thyroid hormone receptor interactor 10; thyroid receptor-interacting protein 10; TR-interacting protein 10; TRIP10; TRIP-10
Gene Symbols Trip10
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 246-545 of human TRIP10 (NP_004231.1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 106628, 9322
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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