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Invitrogen™ TRIP10 Polyclonal Antibody
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Catalog No. PIPA565319
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100 μL
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PIPA565319 100 μL
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Catalog No. PIPA565319 Supplier Invitrogen™ Supplier No. PA565319
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LQRFNRDQAHF YFSQMPQIFD KLQDMDERRA TRLGAGYGLL SEAELEVVPI IA Highest antigen sequence identity to the following orthologs - mouse 96%, rat 89%.

Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling. Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRIP10
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Trip10
Gene Accession No. Q15642
Gene Alias AI646975; Cdc42 interacting protein-4; cdc42-interacting protein 4; Cip4; hSTP; protein Felic; Salt tolerant protein; salt tolerator; STOT; STP; thyroid hormone receptor interactor 10; thyroid receptor-interacting protein 10; TR-interacting protein 10; TRIP10; TRIP-10
Gene Symbols Trip10
Host Species Rabbit
Immunogen Recombinant Human TRIP10. Recombinant protein control fragment (Product #RP-106020).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9322
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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