Invitrogen™ TRIP230 Polyclonal Antibody

Mouse Polyclonal Antibody

Supplier:  Invitrogen™ PA585848

Catalog No. PIPA585848

Description

Keep as concentrated solution. Positive Control: MCF7, HBL100, T24.

The Trip230 gene encodes a protein of 1,978 amino acids with an estimated molecular mass of 230 kDa. The gene is located on chromosome 14q31, which is in a region associated with genetic alterations and thyroid hormone response abnormalities. The Trip230 protein interacts with Rb and thyroid hormone receptor (TR) using two distinct domains. Complex formation with Rb is in a hormone independent manner, but when Trip230 forms a complex with TR, it is in a thyroid hormone-dependent manner. After T3 treatment, Trip230 is phosphorylated and transported to the nucleus, suggesting that phosphorylation may be important for its nuclear translocation.

Specifications

• Antigen: TRIP230
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TRIP11
• Gene Alias: ACG1A; CEV14; clonal evolution-related gene on chromosome 14 protein; GMAP210; GMAP-210; golgi-associated microtubule-binding protein 210; Golgi-microtubule-associated protein of 210 kDa; thyroid hormone receptor interactor 11; thyroid receptor-interacting protein 11; TR-interacting protein 11; TRIP11; TRIP-11; Trip230
• Host Species: Mouse
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunoprecipitation, Western Blot
• Concentration: Conc. Not Determined
• Formulation: Whole serum, PBS with no preservative; pH 7.4
• Gene Accession No.: Q15643
• Gene Symbols: TRIP11
• Immunogen: Amino acids 1099-1372 of Trip230 expressed in E. coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 9321
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov