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Invitrogen™ TRK fused gene Polyclonal Antibody
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Catalog No. 01675296
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100 μg
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Catalog No. Quantity
01-675-296 100 μg
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Catalog No. 01-675-296 Supplier Invitrogen™ Supplier No. PA141468
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Description

Rabbit Polyclonal Antibody

Immunogen sequence homology: Opossum (88%), Chicken (82%).

TFG protein, a recently identified novel protein, is a human homolog of mouse TFG protein. It contains an N-terminal coiled-coil structure, a SPYGQ-rich region followed by octicosapeptide repeats. Research shows that TFG can modulate SHP-1 activity and is a novel member of the NF-kB pathway. The physiological functions of this protein remain largely elusive, but TFG is thought to function by associating with other proteins, including TANK and NEMO. TFG was first identified as a partner of NTRK1 and is involved in generating the thyroid TRK-T3 oncogene, as well as oncogenic rearrangements with ALK in anaplastic lymphoma and NOR1 in mixoid chondrosarcoma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRK fused gene
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide
Gene TFG
Gene Accession No. Q92734
Gene Alias AI173908; HMSNP; protein TFG; SPG57; TF6; TFG; Trk-fused gene; TRK-fused gene protein; TRKT3; TRKT3 oncogene
Gene Symbols TFG
Host Species Rabbit
Immunogen A portion of amino acids 350-400 of human TFG.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10342, 360709
Target Species Human, Rat, Monkey
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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