Invitrogen™ TRK fused gene Recombinant Rabbit Monoclonal Antibody (0V5P10)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA537850

Catalog No. PIMA537850

Description

Positive Samples: Jurkat, Mouse testis, Mouse brain Immunogen sequence: APAFSGQPQQ LPAQPPQQYQ ASNYPAQTYT AQTSQPTNYT VAPASQPGMA PSQPGAYQPR PGFTSLPGST MTPPPSGPNP YARNRPPFGQ GYTQPGPGYR.

TFG protein, a recently identified novel protein, is a human homolog of mouse TFG protein. It contains an N-terminal coiled-coil structure, a SPYGQ-rich region followed by octicosapeptide repeats. Research shows that TFG can modulate SHP-1 activity and is a novel member of the NF-kB pathway. The physiological functions of this protein remain largely elusive, but TFG is thought to function by associating with other proteins, including TANK and NEMO. TFG was first identified as a partner of NTRK1 and is involved in generating the thyroid TRK-T3 oncogene, as well as oncogenic rearrangements with ALK in anaplastic lymphoma and NOR1 in mixoid chondrosarcoma.

Specifications

• Antigen: TRK fused gene
• Classification: Recombinant Monoclonal
• Concentration: 0.33 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q92734
• Gene Symbols: TFG
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 301-400 of human TRK fused gene (TFG) (Q92734).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 0V5P10
• Conjugate: Unconjugated
• Gene: TFG
• Gene Alias: AI173908; HMSNP; protein TFG; SPG57; TF6; TFG; Trk-fused gene; TRK-fused gene protein; TRKT3; TRKT3 oncogene
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10342, 21787, 360709
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov