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Invitrogen™ TrkA Monoclonal Antibody (6B2)
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Catalog No. PIMA515509
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100 μL
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PIMA515509 100 μL
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Catalog No. PIMA515509 Supplier Invitrogen™ Supplier No. MA515509
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Mouse Monoclonal Antibody

MA5-15509 targets TrkA in indirect ELISA, IF and WB applications and shows reactivity with Human samples. The MA5-15509 immunogen is purified recombinant extracellular fragment of human TrkA (aa33-423) fused with hIgGFc tag expressed in HEK293 cell line. MA5-15509 detects TrkA which has a predicted molecular weight of approximately 87.4kDa.

NTRK1 (TRKA) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TrkA
Applications ELISA, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 6B2
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene Ntrk1
Gene Accession No. P04629
Gene Alias C80751; DKFZp781I14186; EC 2.7.10.1; gp140trk; high affinity nerve growth factor receptor; kinase TrkA; MTC; neurotrophic receptor tyrosine kinase 1; Neurotrophic tyrosine kinase receptor type 1; neurotrophic tyrosine kinase, receptor, type 1; Ntrk1; Oncogene TRK; p140-TrkA; Slow nerve growth factor receptor; Tkr; TRK; TRK1; TRK1-transforming tyrosine kinase protein; Trka; Trk-A; TrkA neurotrophin receptor; trkA proto-oncogene receptor; tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A
Gene Symbols Ntrk1
Host Species Mouse
Immunogen Purified recombinant extracellular fragment of human TrkA (aa33-423) fused with hIgGFc tag expressed in HEK293 cell line.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4914
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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