TROP-2 Antibody (TACSTD2/2151) - Azide and BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP275744

Catalog No. NBP275744

Description

TROP-2 Monoclonal specifically detects TROP-2 in Human samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.

Specifications

• Antigen: TROP-2
• Classification: Monoclonal
• Concentration: 0.2 mg/ml
• Dilution: Western Blot 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml
• Gene Accession No.: P09758
• Gene Symbols: TACSTD2
• Immunogen: Recombinant fragment of human TROP-2 protein (around aa 31-274) (exact sequence is proprietary) (Uniprot: P09758 )
• Purification Method: Protein A or G purified
• Research Discipline: Signal Transduction
• Gene ID (Entrez): 4070.0
• Target Species: Human
• Form: Purified

• Applications: Western Blot, Immunohistochemistry (Paraffin)
• Clone: TACSTD2/2151
• Conjugate: Unconjugated
• Formulation: 10 mM PBS with No Preservative
• Gene Alias: Cell surface glycoprotein Trop-2, EGP1, EGP-1, epithelial glycoprotein-1, GA733-1GP50, gastrointestinal tumor-associated antigen GA7331, M1S1cell surface glycoprotein TROP2, Membrane component chromosome 1 surface marker 1, membrane component, chromosome 1, surface marker 1, Pancreatic carcinoma marker protein GA733-1, pancreatic carcinoma marker protein GA7331,40kD glycoprotein, identified by monoclonal GA733, TROP2GA7331, tumor-associated calcium signal transducer 2
• Host Species: Mouse
• Molecular Weight of Antigen: 40 kDa
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: TROP-2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.
• Content And Storage: Store at 4°C.
• Isotype: IgG2b κ