Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Troponin I Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

$209.50 - $511.50

Specifications

Antigen Troponin I
Concentration 0.5 mg/mL
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
PIPA5121541
View Documents
Invitrogen™
PA5121541
20 μL
Each for $209.50
Only null left
Add to Cart
 
PIPA5121540
View Documents
Invitrogen™
PA5121540
100 μL
Each for $511.50
Only null left
Add to Cart
 
Description

Description

Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.
Specifications

Specifications

Troponin I
Western Blot
Unconjugated
Rabbit
Human, Mouse
P19237, P19429, P48787, Q9WUZ5
21952, 21954, 7135, 7137
Met1-Asp103 linked with Leu142-Gln187 (Accession P19237), with N-terminal His Tag.
Primary
-20°C
0.5 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.05% ProClin 300
2700018B22Rik; AI747285; Cardiac troponin I; cardiomyopathy, dilated 2A (autosomal recessive); CMD1FF; CMD2A; CMH7; cTNI; DKFZp451O223; RCM1; slow skeletal troponin I isoform; ssTnI; Tn1; TnI; TNN1; TNNC1; TNNI1; TNNI3; Tpn1; troponin 1, type 3; troponin I type 1 (skeletal, slow); troponin I type 3 (cardiac); troponin I, cardiac 3; troponin I, cardiac muscle; troponin I, skeletal, slow; troponin I, skeletal, slow 1; Troponin I, slow isoform; troponin I, slow skeletal; troponin I, slow skeletal muscle; Troponin I, slow-twitch isoform; troponin I1, slow skeletal type; troponin I3, cardiac type
TNNI1, TNNI3
IgG
Antigen affinity chromatography
Antibody
Videos
SDS
Documents

Documents

Product Certifications
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.