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Invitrogen™ TROY Polyclonal Antibody
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Catalog No. 01676658
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100 μg
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Catalog No. Quantity
01-676-658 100 μg
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Catalog No. 01-676-658 Supplier Invitrogen™ Supplier No. PA141061
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Description

Rabbit Polyclonal Antibody

In Western blot, this antibody detects a band at ~46 kDa (predicted molecular weight 50.8 kDa. For optimal results, primary antibody incubations should be performed at room temperature. Suggested positive control: antigen standard for TNFRSF19 (transient overexpression lysate), T98G.

Tumor necrosis factor receptor superfamily member 19, commonly known as TROY, is a gene located on chromosome 1p36.22 that encodes a member of the tumor necrosis factor receptor (TNFR) superfamily. TROY is expressed in the nervous system, skin, and various tissues, where it plays a role in regulating cell apoptosis, inflammation, and development. As a receptor, TROY interacts with ligands and other signaling molecules to modulate pathways involved in cell survival, differentiation, and immune responses. In the context of the nervous system, TROY has been implicated in axonal outgrowth and regeneration, particularly influencing signaling pathways related to neural development and repair. Additionally, TROY has been studied in cancer research due to its potential role in tumor growth and progression, making it a candidate for therapeutic targeting. Its involvement in diverse biological processes highlights its significance in maintaining cellular homeostasis and its potential as a therapeutic target in neurobiology and oncology.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TROY
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide
Gene Tnfrsf19
Gene Accession No. Q9JLL3, Q9NS68
Gene Alias AL023044; AW123854; RGD1564996; TAJ; TAJ-alpha; TNF receptor superfamily member 19; Tnfrsf19; Toxicity and JNK inducer; TRADE; TROY; tumor necrosis factor receptor superfamily member 19; tumor necrosis factor receptor superfamily, member 19; UNQ1888/PRO4333
Gene Symbols Tnfrsf19
Host Species Rabbit
Immunogen Mixture of synthetic peptides corresponding to amino acids 29-44, 204-219, and 409-421 of human TROY.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29820, 55504
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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