Invitrogen™ TROY Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA141061

Catalog No. 01-676-658

Description

In Western blot, this antibody detects a band at ~46 kDa (predicted molecular weight 50.8 kDa. For optimal results, primary antibody incubations should be performed at room temperature. Suggested positive control: antigen standard for TNFRSF19 (transient overexpression lysate), T98G.

Tumor necrosis factor receptor superfamily member 19, commonly known as TROY, is a gene located on chromosome 1p36.22 that encodes a member of the tumor necrosis factor receptor (TNFR) superfamily. TROY is expressed in the nervous system, skin, and various tissues, where it plays a role in regulating cell apoptosis, inflammation, and development. As a receptor, TROY interacts with ligands and other signaling molecules to modulate pathways involved in cell survival, differentiation, and immune responses. In the context of the nervous system, TROY has been implicated in axonal outgrowth and regeneration, particularly influencing signaling pathways related to neural development and repair. Additionally, TROY has been studied in cancer research due to its potential role in tumor growth and progression, making it a candidate for therapeutic targeting. Its involvement in diverse biological processes highlights its significance in maintaining cellular homeostasis and its potential as a therapeutic target in neurobiology and oncology.

Specifications

• Antigen: TROY
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tnfrsf19
• Gene Alias: AL023044; AW123854; RGD1564996; TAJ; TAJ-alpha; TNF receptor superfamily member 19; Tnfrsf19; Toxicity and JNK inducer; TRADE; TROY; tumor necrosis factor receptor superfamily member 19; tumor necrosis factor receptor superfamily, member 19; UNQ1888/PRO4333
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 29820, 55504
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.05% BSA and 0.05% sodium azide
• Gene Accession No.: Q9JLL3, Q9NS68
• Gene Symbols: Tnfrsf19
• Immunogen: Synthetic peptides corresponding to residues 29-44, 204-219, and 409-421 of human TROY.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG