Invitrogen™ TROY Recombinant Rabbit Monoclonal Antibody (208)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA529836

Catalog No. PIMA529836

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Mouse TNFRSF19.

Tumor necrosis factor receptor superfamily member 19, commonly known as TROY, is a gene located on chromosome 1p36.22 that encodes a member of the tumor necrosis factor receptor (TNFR) superfamily. TROY is expressed in the nervous system, skin, and various tissues, where it plays a role in regulating cell apoptosis, inflammation, and development. As a receptor, TROY interacts with ligands and other signaling molecules to modulate pathways involved in cell survival, differentiation, and immune responses. In the context of the nervous system, TROY has been implicated in axonal outgrowth and regeneration, particularly influencing signaling pathways related to neural development and repair. Additionally, TROY has been studied in cancer research due to its potential role in tumor growth and progression, making it a candidate for therapeutic targeting. Its involvement in diverse biological processes highlights its significance in maintaining cellular homeostasis and its potential as a therapeutic target in neurobiology and oncology.

Specifications

• Antigen: TROY
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7
• Gene Accession No.: Q9JLL3
• Gene Symbols: Tnfrsf19
• Immunogen: Recombinant Mouse TNFRSF19 protein (Met1-Leu170).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA
• Clone: 208
• Conjugate: Unconjugated
• Gene: Tnfrsf19
• Gene Alias: AL023044; AW123854; RGD1564996; TAJ; TAJ-alpha; TNF receptor superfamily member 19; Tnfrsf19; Toxicity and JNK inducer; TRADE; TROY; tumor necrosis factor receptor superfamily member 19; tumor necrosis factor receptor superfamily, member 19; UNQ1888/PRO4333
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 29820
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid