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Invitrogen™ TRPC3 Polyclonal Antibody
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Catalog No. PIPA5116077
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PIPA5116077 100 μL
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Catalog No. PIPA5116077 Supplier Invitrogen™ Supplier No. PA5116077
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total TRPC3.

The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the canonical TRP (TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors. TRPC3 encodes a Ca2+-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. TRPC3 physically interacts with TRPC6 and TRPC7 and forms functional tetrameric channels.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRPC3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene Trpc3
Gene Accession No. Q13507, Q9JMI9, Q9QZC1
Gene Alias hTrp3; hTrp-3; ion channel protein; mTrp3; Mwk; receptor-activated cation channel TRP3; SCA41; Short transient receptor potential channel 3; transient receptor potential cation channel subfamily C member 3; transient receptor potential cation channel subfamily C member 3 variant c; transient receptor potential cation channel, subfamily C, member 3; transient receptor protein 3; Trcp3; Trp3; TRP-3; TRPC3; TrpC3c; trp-related protein 3; Trrp3
Gene Symbols Trpc3
Host Species Rabbit
Immunogen A synthesized peptide derived from human TRPC3(Accession Q13507), corresponding to amino acid residues N784-R834.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22065, 60395, 7222
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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