Invitrogen™ TRPC3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116077

Catalog No. PIPA5116077

Description

Antibody detects endogenous levels of total TRPC3.

The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the canonical TRP (TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors. TRPC3 encodes a Ca2+-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. TRPC3 physically interacts with TRPC6 and TRPC7 and forms functional tetrameric channels.

Specifications

• Antigen: TRPC3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Trpc3
• Gene Alias: hTrp3; hTrp-3; ion channel protein; mTrp3; Mwk; receptor-activated cation channel TRP3; SCA41; Short transient receptor potential channel 3; transient receptor potential cation channel subfamily C member 3; transient receptor potential cation channel subfamily C member 3 variant c; transient receptor potential cation channel, subfamily C, member 3; transient receptor protein 3; Trcp3; Trp3; TRP-3; TRPC3; TrpC3c; trp-related protein 3; Trrp3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22065, 60395, 7222
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q13507, Q9JMI9, Q9QZC1
• Gene Symbols: Trpc3
• Immunogen: A synthesized peptide derived from human TRPC3(Accession Q13507), corresponding to amino acid residues N784-R834.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG